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Patulin Impairs Human SVOG Granulosa Cells via ROS-Mediated DNA Damage and ATM-p53 Activation

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NIAID Data Ecosystem2026-05-10 收录
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This study investigates the toxic effects of patulin on human granulosa SVOG cells. Patulin exposure induced ROS accumulation, DNA damage, and activation of the ATM-p53 pathway, leading to G2/M cell-cycle arrest and apoptosis, suggesting potential risks to female reproductive health.

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2026-03-14
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