Effects of CPL207280 and TAK-875 on pivotal hepatocyte health markers.

NIAID Data Ecosystem2026-03-12 收录

数据链接：

https://figshare.com/articles/dataset/Effects_of_CPL207280_and_TAK-875_on_pivotal_hepatocyte_health_markers_/16671434 数据链接链接失效反馈

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Effects of CPL207280 and TAK-875 on pivotal hepatocyte health markers.

创建时间：

2021-09-23

Characterization of Triptolide-Induced Hepatotoxicity by Imaging and Transcriptomics in a Novel Zebrafish Model [miRA-seq]

药物肝毒性

斑马鱼毒理模型

Zebrafish larvae treated with triptolide (5 dpf larvae after exposure to triptolide (1.6μM) for 6 hours) or vehicle control. A total of 16 sequencing experiments were performed (control N=8 and treatm

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3'mRNA sequencing of hepatic RNA (MACE) at the time points 24h/48h after acetaminophen (APAP) (300mg/kg) administration

药物肝毒性

RNA测序分析

Hepatic RNA specimens from mice (C57BL/6) of the 4 groups (vehicle-treated at 24h/48h, n=6; acetaminophen (APAP)-treated (300mg/kg) at 24h/48h, n=7) were pooled at equal shares. Thereafter, pooled RNA

NIAID Data Ecosystem40

Gene expression data from primary human hepatocytes treated with GGF2 for 6, 24, or 72 h or 24 h with a 48 h washout.

药物肝毒性

基因表达谱分析

GGF2 is a recombinant human neuregulin-1β in development for chronic heart failure. Phase 1 clinical trials of GGF2 were put on hold when transient elevations in serum aminotransferases and total bili

NIAID Data Ecosystem40

Effects of Methotrexate (MTX) and Sitagliptin (Sita) on oxidative stress markers in the liver.

药物肝毒性

氧化应激标志物

Effects of Methotrexate (MTX) and Sitagliptin (Sita) on oxidative stress markers in the liver.

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Hepatotoxicity of isotretinoin in patients with acne and Gilbert's syndrome: comparative study

药物肝毒性

吉尔伯特综合征治疗

Objectives: The objective of our follow-up study is to evaluate liver function tests (LFTs) and lipid profiles in patients with Gilbert's syndrome treated with isotretinoin because of severe acne. Set

NIAID Data Ecosystem40

Effects of CPL207280 and TAK-875 on pivotal hepatocyte health markers.

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