Cryo-EM structure of the human TRPV4 - RhoA in complex with GSK2798745
收藏Protein Data Bank Japan2024-06-19 更新2026-06-30 收录
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Cryo-EM structure of the human TRPV4 - RhoA in complex with GSK2798745 Descriptor: 1-({(5S,7S)-3-[5-(2-hydroxypropan-2-yl)pyrazin-2-yl]-7-methyl-2-oxo-1-oxa-3-azaspiro[4.5]decan-7-yl}methyl)-1H-benzimidazole-6-carbonitrile, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Kwon, D.H, Lee, S.-Y, Zhang, F. Deposit date: 2022-12-01 Release date: 2023-07-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease. Nat Commun, 14, 2023
创建时间:
2022-12-01



