Huntington's disease (HD) is a fatal, dominantly inherited neurodegenerative disorder caused by a CAG trinucleotide expansion in exon 1 of the huntingtin (HTT) gene. Although the pathogenesis of HD re

NIAID Data Ecosystem30

Effects on Murine Behavior and Lifespan of Selectively Decreasing Expression of Mutant Huntingtin Allele by Supt4h Knockdown

亨廷顿病治疗

神经退行性疾病模型

Production of protein containing lengthy stretches of polyglutamine encoded by multiple repeats of the trinucleotide CAG is a hallmark of Huntington’s disease (HD) and of a variety of other inherited

NIAID Data Ecosystem10

AAV-CYP46A1 gene therapy in mouse models of Huntington’s disease. AAV-CYP46A1 gene therapy in mouse models of Huntington’s disease

亨廷顿病治疗

RNA-seq转录组学

To evaluate the effect of CYP46A1 treatment in R6/2 mice, we performed gene expression profiling analysis using data obtained from RNA-seq of 6 different conditions Overall design: To evaluate the eff

NIAID Data Ecosystem30

North America Huntingtons Disease Therapeutics Market

亨廷顿病治疗

区域市场分析

The North America Huntingtons Disease Therapeutics report features an extensive regional analysis, identifying market penetration levels across major geographic areas. It highlights regional growth tr

IMR REPORTS20

Diagnostic properties of the Frontal Assessment Battery (FAB) in Huntington's disease

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