Structure of thermolysin in complex with inhibitor (JC306).

Structure of thermolysin in complex with inhibitor (JC306). Descriptor: (2~{S})-2-[[(2~{S})-3-azanyl-2-[[oxidanyl(phenylmethoxycarbonylaminomethyl)phosphoryl]amino]propanoyl]amino]-4-methyl-pentanoic acid, CALCIUM ION, DIMETHYL SULFOXIDE, ... Authors: Krimmer, S.G, Cramer, J, Heine, A, Klebe, G. Deposit date: 2016-11-03 Release date: 2017-08-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.3 Å) Cite: How Nothing Boosts Affinity: Hydrophobic Ligand Binding to the Virtually Vacated S1' Pocket of Thermolysin. J. Am. Chem. Soc., 139, 2017