The negative effects of inbreeding on fitness are serious concerns for populations of endangered species. Reduced fitness has been associated with lower genome-wide heterozygosity and immune gene dive

DataONE2020-06-24 更新50

Trans-Species Polymorphism and Selection in the MHC Class II DRA Genes of Domestic Sheep

免疫遗传学

分子进化

Highly polymorphic genes with central roles in lymphocyte mediated immune surveillance are grouped together in the major histocompatibility complex (MHC) in higher vertebrates. Generally, across verte

NIAID Data Ecosystem30

MHC allele numbers.

种群遗传学

免疫遗传学

Kruskal-Wallis test for equal medians and following Dunn’s posthoc test. Dunn’s z values above the diagonal, Bonferroni corrected p-values below the diagonal. Significant p-values are marked in bold t

NIAID Data Ecosystem20

The association between HLA-DRB1 alleles and antibody response to individual antigens.

免疫遗传学

抗体反应

The association between HLA-DRB1 alleles and antibody response to individual antigens.

NIAID Data Ecosystem30

SARS-CoV-2 BA.1 and BA.2 breakthrough infections boost antibody responses to early Omicron subvariants but not BQ.1.1 and XBB.1.5

病毒学

免疫学

Here, the authors describe the potency and breadth of neutralizing and binding antibody responses against a large panel of VOC following an Omicron BA.1 or BA.2 breakthrough infection.

DataCite Commons2024-03-22 更新20

Development of Ferret Reference Resources and Profiling Assays.

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