A Convergent Coordination Chemistry-Based Approach to Dissymmetric Macrocyclic Cofacial Porphyrin Complexes

We report a highly convergent and modular approach for the
synthesis of dissymmetric cofacial porphyrin complexes, which is
based upon the weak-link approach to supramolecular coordination
chemistry. Specifically, we have utilized a halide-induced ligand
rearrangement reaction, which is capable of providing heteroligated
mixed-metal porphyrin complexes in quantitative yield. Significantly,
the adoption of a coordination chemistry based approach for the
synthesis of these complexes allows for facile in situ regulation of
the porphyrin−porphyrin interactions through the addition of external
chemical stimuli.