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Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function. Mus musculus

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Using RNAseq we describe transcriptional changes downstream of liver-specific knockout of RNaseH1, including effects on mitochondrial function, fibrosis and cell cycle Overall design: We perform RNAseq on mouse livers under conditions of constitutive or inducible knockout of RNaseH1

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2017-06-05
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