Additional file 1 of Monocyte, neutrophil, and whole blood transcriptome dynamics following ischemic stroke

Additional file 1: Table S1. Differentially expressed genes (DEGs) significant to time point (TP) p-value < 0.02 on the contrasts IS TP vs. VRFC (TP0). Table S2. Enriched canonical pathways overrepresented in all time points (TP) (Fisher's p-value < 0.05). Table S3. Predicted upstream regulators in all time points (TP) (Fishers' p-value < 0.05). Table S4. Differentially expressed genes (DEGs) distributed per GEDI map tile based on Pearson's correlation of gene expression values. Table S5. Differentially expressed genes (DEGs) distributed per SOM profile based on Euclidean distance. Table S6. GO terms for biological processes enriched in the SOM profiles from Fig. 6. Table S7. Subject demographics and relevant clinical characteristics in the time bins analyzed after regrouping per IS etiology. Table S8. Differentially expressed genes (DEGs) significant to time point (TP) p-value < 0.02 on the contrasts IS TP-IS etiology vs. VRFC (TP0). Table S9. DEGs distributed per SOM profile in all IS etiologies, based on Euclidean distance. Table S10. GO terms for biological processes enriched in the SOM profiles from Fig. 9, for all IS etiologies. Table S11. Genes in WGCNA modules associated time (h). Table S12. Hub genes in the modules significant to time (h). Table S13. HumanBase functional clustering of hub genes from time-associated modules and their corresponding gene ontology terms. Table S14. Correlation between NIHSS at admission and expression of time-associated hub genes.