EPI-CT scan cohort

EPI-CT is a multinational cohort study of children and young adults who have undergone at least one computed tomography (CT) scan before the age of 22 years. It comprises three main parts: 1) an epidemiological cohort study assessing cancer effects of radiation exposure from CT; 2) a dosimetry system to evaluate individual doses and related uncertainty, and supporting dose reduction and optimisa on strategies; 3) a pilot study to evaluate the feasibility of applying diferent biomarkers of hypersensitivity in young patients exposed to low doses from CT.
Cohort type:
International cohort comprising 1,163,571 patients from BE, DK, FR, DE, NL, NO, ES, SE and GB, who have undergone CT examination.
Age/follow-up:
- age at exposure: from 0 to 22 years
- mean age at the first examination: 10 years,
-mean age at the end of cur- rent follow-up: 20 years
- follow-up period varies by country and ranges from 1973 to 2015
Data available:
-Individual organ doses due to external X-ray irradiation, including uncertainty analy-sis;
- cancer incidence;
-vital status (except in Ger-many and partially in FR; -socioeconomic status availa-ble in BE, FR, NL, ES and GB -cancer predisposing syndromes available in FR, NL and NO.