Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydro-pyridinone inhibitor
收藏Protein Data Bank Japan2024-04-03 更新2026-03-21 收录
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Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydro-pyridinone inhibitor Descriptor: N-{3-[(6S)-6-ethyl-1-(4-fluorobenzyl)-4-hydroxy-2-oxo-1,2,5,6-tetrahydropyridin-3-yl]-1,1-dioxido-2H-1,2,4-benzothiadiazin-7-yl}methanesulfonamide, RNA-DIRECTED RNA POLYMERASE Authors: Zhao, Q, Showalter, R.E, Han, Q, Kissinger, C.R. Deposit date: 2009-07-28 Release date: 2009-12-08 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.6 Å) Cite: 5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg.Med.Chem.Lett., 19, 2009
创建时间：
2009-07-28
