The co-evolution trends of amino acids within or between genes offer valuable insights into protein structure and function. Existing tools for uncovering co-evolutionary signals primarily rely on mult
Supplementary files for the paper: Coevolution of residues provides evidence of a functional heterodimer of 5-HT2AR and 5-HT2CR involving both intracellular and extracellular domains
Mutations in the GBA1 gene are associated with increased risk of Parkinson's disease, and the protein produced by the gene, glucocerebrosidase, interacts with α-synuclein, the protein at the center of
