Crystal structure of Hsp90-alpha N-terminal domain in complex with 2-(4-Hydroxy-cyclohexylamino)-4-[5-(4-phenyl-imidazol-1-yl)-isoquinolin-1-yl]-benzamide
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Crystal structure of Hsp90-alpha N-terminal domain in complex with 2-(4-Hydroxy-cyclohexylamino)-4-[5-(4-phenyl-imidazol-1-yl)-isoquinolin-1-yl]-benzamide Descriptor: 2-[(trans-4-hydroxycyclohexyl)amino]-4-[5-(4-phenyl-1H-imidazol-1-yl)isoquinolin-1-yl]benzamide, Heat shock protein HSP 90-alpha Authors: Chong, K.T, Yamashita, S, Oshiumi, H, Uno, T, Kitade, M. Deposit date: 2014-01-23 Release date: 2015-02-25 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Evolution of highly selective Hsp90 / inhibitors by structure and thermodynamics guided design To be Published
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2014-01-23
