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IEAtlas

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国家生物信息中心2025-10-11 更新2025-03-15 收录
下载链接:
http://bio-bigdata.hrbmu.edu.cn/IEAtlas
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资源简介:
IEAtlas reanalyzed publicly available mass spectrometry-based HLA immunopeptidome datasets against our integrated benchmarked non-canonical open reading frame information. The current IEAtlas identified 245 870 non-canonical epitopes binding to HLA-I/II allotypes across 15 cancer types and 30 non-cancerous tissues, greatly expanding the cancer immunopeptidome. IEAtlas further evaluates the immunogenicity via several commonly used immunogenic features, including HLA binding affinity, stability and T-cell receptor recognition. In addition, IEAtlas provides the biochemical properties of epitopes as well as the clinical relevance of corresponding genes across major cancer types and normal tissues.
提供机构:
Harbin Medical University
创建时间:
2023-08-23
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