The influence of upper interface T248 and L249 mutations on activation gating of the Shaker Kv channela

Fig. 2.a The table displays the gating parameters of all single- and double-mutants used to assess the effect of T248 and or L249 mutation on channel maturation and gating, as addressed in b Mutants were generated using a monomeric gene construct such that all four subunits carry the indicated mutation.