Scalable Synthesis of Cyclocitrinol
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https://figshare.com/articles/dataset/Scalable_Synthesis_of_Cyclocitrinol/6840188
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资源简介：
A 10-step
synthesis of the C25 steroid natural product cyclocitrinol
from inexpensive, commercially available pregnenolone is reported.
This synthesis features a biomimetic cascade rearrangement to efficiently
construct the challenging bicyclo[4.4.1] A/B ring system, which enabled
a gram-scale synthesis of the bicyclo[4.4.1] enone intermediate 18 in only nine steps. This work also provides experimental
support for the biosynthetic origin of cyclocitrinol.
创建时间：
2018-07-19
