Cobalt-Catalyzed Trifluoromethoxylation of Epoxides

A catalytic ring-opening
reaction of epoxides by nucleophilic trifluoromethoxylation
of trifluoromethyl arylsulfonate has been developed based on the use
of a cobalt catalyst. This reaction provides an efficient, simple
route for directly construction of a wide range of vicinal trifluoromethoxyhydrins
under mild conditions. In addition, this method can convert terminal
epoxides into target products with good chemo- and regioselectivity.