AIMaP
收藏国家生物信息中心2025-10-11 更新2025-03-15 收录
下载链接：
https://mvip.whu.edu.cn/aimap
下载链接
链接失效反馈官方服务：
资源简介：
Integrating the protein- and RNA-interactomes, we found that SARS-CoV-2 RNA and its N protein closely interacted with stress granules including 40 core factors, of which we specifically validated G3BP1, IGF2BP1, and MOV10 using RIP and Co-IP assays. Combining CRISPR screening results, we further identified 86 antiviral and 62 proviral factors and associated drugs. Using network diffusion, we found additional 44 interacting proteins including two proviral factors previously validated. Furthermore, we showed that this atlas could be applied to identify the complications associated with COVID-19.
提供机构：
Wuhan University
创建时间：
2023-08-23
