The demographic, clinical and pathological parameters of patients with anti-GBM disease.

SCr: serum creatinine, ANCA: anti-neutrophil cystoplasmic antibodies, FRA: fibrinogen related antigens, Alb: albumin, GCW: glomerular capillary wall, Ms: mesangium. This study included two patients with negative staining for linear IgG, possibly because of the severe destruction of glomerular capillary walls. The diagnosis was confirmed by the detection of anti-GBM IgG in serum and linear IgG staining on paraffin tissue by immunofluorescence.