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Crystal structure of human Carbonic anhydrase II in complex with (R)-4-(2-benzyl-4-methylpiperazin-1-yl)benzenesulfonamide

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Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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Crystal structure of human Carbonic anhydrase II in complex with (R)-4-(2-benzyl-4-methylpiperazin-1-yl)benzenesulfonamide Descriptor: 4-[(3~{S})-4-methyl-3-(phenylmethyl)piperazin-1-yl]carbonylbenzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ... Authors: Ferraroni, M, Angeli, A, Supuran, C. Deposit date: 2019-04-16 Release date: 2020-05-13 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Sulfonamides incorporating piperazine bioisosteres as potent human carbonic anhydrase I, II, IV and IX inhibitors. Bioorg.Chem., 91, 2019
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2019-04-16
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