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资源简介：
Transcription profiling by high throughput sequencing of mice with a partial or complete deletion of Ezh2 in regulatory T cells
应用场景：
创建时间：
2019-05-14
相关数据集
Transcription profile of WT and LKB1 (encoded by the gene Stk11)-deficient Treg cells
LKB1 deficiency in Treg cells impairs their survival, metabolism and suppressive function. To exclude the impact of excessive inflammation on LKB1-deficient Treg cells, we generated mixed bone marrow
NIAID Data Ecosystem20
MiRNome and transcriptome aided pathway analysis in human regulatory T cells. Homo sapiens
Owing to their manifold immune regulatory functions, regulatory T cells (Treg) have received tremendous interests as targets for therapeutic intervention of diverse immunological pathologies or cancer
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Next Generation Sequencing of Transcriptomes of WT and Transgenic Treg cells to differentiate effect of TIM-3 on Tregulatory cell geneexpression.
Significant differences were found in transcriptional profiles of WT and TIM-3+(GFPHi and GFP Low) cells, suggesting major shifts in metabolic status, cytokine profiles and suppresive capacity of Treg
NIAID Data Ecosystem20
Impaired regulatory T cell-dendritic cell interactions contribute to autoimmunity in leukocyte adhesion deficiency type-1. Impaired regulatory T cell-dendritic cell interactions contribute to autoimmunity in leukocyte adhesion deficiency type-1
RFP reporter protein expressing splenic regulatory T cells (Treg) were isolated by flow cytometry from mice with a Foxp3-specific knockdown of CD18 (n=3) and the according control mice (n=3). Aliquots
NIAID Data Ecosystem20
RNA-sequencing on sorted Nrn1-/- and Nrn1+/- effector Treg cells
Nrn1-/- and Nrn1+/- CD4+CD25+Cd62LlowCD44highFoxp3gfp+ were sorted from Nrn1-/- and Nrn1+/- mice on Foxp3DTRgfp background and subjected to RNASeq analysis Expression profiling by high throughput sequ
NIAID Data Ecosystem20
