Gene expression analysis upon TNF stimulation combined with TPCA-1 or MRT67307. Homo sapiens

NIAID Data Ecosystem2026-03-10 收录

TNF信号通路

IKK激酶功能分析

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA422567 数据链接链接失效反馈

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资源简介：

The study aims at determining the function of the IKK-related kinases TBK1 and IKK epsilon in TNF-induced signalling

创建时间：

2017-12-15

Crystal structure of the complex between the N-terminal domain of TRADD and the TRAF domain of TRAF2

蛋白质结构解析

TNF信号通路

Crystal structure of the complex between the N-terminal domain of TRADD and the TRAF domain of TRAF2 Descriptor: TUMOR NECROSIS FACTOR RECEPTOR TYPE 1 ASSOCIATED DEATH DOMAIN PROTEIN, TUMOR NECROSIS F

Protein Data Bank Japan2024-11-13 更新60

Wang et al TNFR1 signaling connects inflammation to impaired fatty acid oxidation to drive intestinal stem cell aging Supporting data and code

干细胞衰老

TNF信号通路

Files contain raw R code for RNAseq analysis in intestinal organoids obtained from young mice and either treated with vehicle, or TNF at a dose of 10 or 50ng/mL. Old vehicle treated are also included.

NIAID Data Ecosystem20

Multi-omics approaches reveal TNF-mediated inhibition of tissue reparative macrophages is via a gene-selective transcriptional mechanism (ATAC-Seq). Multi-omics approaches reveal TNF-mediated inhibition of tissue reparative macrophages is via a gene-selective transcriptional mechanism (ATAC-Seq)

巨噬细胞调控

TNF信号通路

Anti-TNF therapies are a core anti-inflammatory approach for chronic diseases such as rheumatoid arthritis and Crohn’s Disease. Previously, we and others found that TNF blocks the emergence and functi

NIAID Data Ecosystem20

Alterations in tumour necrosis factor signaling pathways associated with cytotoxicity and resistance to taxanes in tumour cells.

紫杉烷耐药机制

TNF信号通路

The taxanes are widely used in the treatment of breast and other cancers. While their cytotoxicity has been attributed to the induction of cell cycle arrest in mitosis through the stabilization of mi

NIAID Data Ecosystem30

RNPS1 inhibits excessive TNF/TNFR signaling to support hematopoiesis in mice

干细胞研究

TNF信号通路

Null mutations of spliceosome components or cofactors are homozygous lethal in eukaryotes, but viable hypomorphic mutations provide an opportunity to understand the physiological impact of individual

NIAID Data Ecosystem20

Gene expression analysis upon TNF stimulation combined with TPCA-1 or MRT67307. Homo sapiens

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