Human glucokinase in complex with novel pyrazole activator.
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Human glucokinase in complex with novel pyrazole activator. Descriptor: (2S)-3-cyclohexyl-2-[4-(cyclopentylsulfonyl)-2-oxopyridin-1(2H)-yl]-N-(1,3-thiazol-2-yl)propanamide, Glucokinase, IODIDE ION, ... Authors: Skene, R.J, Hosfiled, D.J. Deposit date: 2017-03-10 Release date: 2017-05-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Discovery of potent and orally active 1,4-disubstituted indazoles as novel allosteric glucokinase activators. Bioorg. Med. Chem. Lett., 27, 2017
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2017-03-10
