Genome-wide epigenome mapping in human induced pluripotent cells in WT and KDM6AKO cells. [RNA-Seq]

KDM6A is a histone demethylase that remove H3K27me3 lysine. This study compares the transcriptomic profile between WT and KDM6A KO cells and further evaluates their functional validation by applying the invitro hematopoietic differentiation protocol. Examination of transcriptomic profile in WT and KDM6A KO cells.