Estrogen receptor β affects hypoxia response in colorectal cancer cells. Estrogen receptor β affects hypoxia response in colorectal cancer cells

Our study identifies pathwyas related to tumour suppressor fuunction of estrogen receptor beta in colon cancer cells under hypoxic conditions. Overall design: Estrogen receptor β, encoded by ESR2, was overexpressed using lentivrial system in HCT116, colon cell line, obtained from ATCC.