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2020-12-28
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BUA GWAS gender-combined meta-analysis summary results
This dataset contains the summary results from a genome-wide association study meta-analysis for broadband ultrasound attenuation (PMID 28472463). Note: only variants present in all three studied coho
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Bone parameters in standardized Z scores averaged over all Q-variants carriers.
N is the number of observations available.*Asterisk indicates sites with data from more than one study combined using Z scores. P value is the test of the hypothesis that the mean Z score is zero. Key
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Association results of forearm BMD meta-analysis and fracture for selected SNPs.
EA: effect allele; NEA: non-effect allele; EAF: effect allele frequency; RA: risk allele.See Table S4 for a list of all genome-wide significant SNPs.
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Change in bone mineral density per copy of the variant allele for individual SNPs which were significant in the multivariable models including clinical risk factors 1 .
Footnote: 1The clinical risk factors included in the multivariable models are: (1) Spinal BMD change after autologous HCT: spinal BMD at baseline and diagnosis (lymphoma vs others); (
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Table_2_Identifying Pleiotropic SNPs Associated With Femoral Neck and Heel Bone Mineral Density.XLSX
BackgroundGenome-wide association studies (GWASs) routinely identify loci associated with risk factors for osteoporosis. However, GWASs with relatively small sample sizes still lack sufficient power t
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