Pregnancy outcome after challenging the pre-pregnancy vaccinated mice with WT.

Vaccination with DV-STM-07 prevents abortion induced by WT challenge during pregnancy. Vaccinated (3 doses) and control mice were mated and challenged with 107 CFU/mouse WT Salmonella during pregnancy (as described in materials and methods). There was no incidence of fetal death in vaccinated mice whereas there was one case of maternal death and two cases of abortion and one fetal resorption in unvaccinated mice. Experiment was repeated thrice to reproduce the observed results. Fisher's exact test was used to analyze the data. p-value = 0.0285.