Supplemental material for: The Cumulative Exposure to High-sensitivity C-reactive Protein Predicts the Risk of Chronic Kidney Diseases

Table S1. Adjusted HRs and 95% CI of Baseline hs-CRP for Endpoint Events by Cox Proportional Hazards Models Note: Baseline hs-CRP, high-sensitivity C-reactive protein in 2006. Table S2. Adjusted HRs and 95% CI of cumhs-CRP for CKD by Cox Proportional Hazards Models in different population Note: CI, confidence interval. P trend, test of trend based on median value in each category for ordinal categorical variables; cumhs-CRP, cumulative high-sensitivity C-reactive protein; CKD, Chronic Kidney Diseases; HR, hazard ratio; *Compared with nonexposed group. Model A: adjusted for age, sex, baseline SBP, BMI, FPG, TC, physical activity, smoking, drinking, and treatment of antihypertensive, antidiabetic, and lipid-lowering medication and 06hs-CRP. cumhs-CRP for CKD by Cox Proportional Hazards Model in Smoke/ Non-smoke population. Model B: adjusted for age, sex, baseline SBP, BMI, FPG, TC, physical activity, smoking, drinking, and treatment of antihypertensive, antidiabetic, and lipid-lowering medication and 06hs-CRP. cumhs-CRP for CKD by Cox Proportional Hazards Model in Hypertension/Non-hypertension population. Model C: adjusted for age, sex, baseline SBP, BMI, FPG, TC, physical activity, smoking, drinking, and treatment of antihypertensive, antidiabetic, and lipid-lowering medication and 06hs-CRP. cumhs-CRP for CKD by Cox Proportional Hazards Model in Diabetes mellitus/Non-diabetes mellitus population. Model D: adjusted for age, sex, baseline SBP, BMI, FPG, TC, physical activity, smoking, drinking, and treatment of antihypertensive, antidiabetic, and lipid-lowering medication and 06hs-CRP. cumhs-CRP for CKD by Cox Proportional Hazards Model in Hyperlipidemia/Non-hyperlipidemia population.