Mus musculus Raw sequence reads

Dietary fructose is associated with non-alcoholic fatty liver disease (NAFLD). Previous studies mainly focused on its direct impacts on de novo lipogenesis in the liver. Recent studies have demonstrated that the gut microbiota and their metabolites bile acids (BAs) play important roles in the pathogenesis of NAFLD. The aim of this study is to explore the influence of dietary fructose on BA metabolism and gut dysbiosis during the development of NAFLD.