Scalable Total Synthesis of (−)-Vinigrol
收藏NIAID Data Ecosystem2026-03-10 收录
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资源简介：
Vinigrol is a structurally and stereochemically complex natural product that displays various potent pharmacological activities, including the capability to modulate TNF-α. A new and efficient synthetic route toward this natural product has been developed to complete the asymmetric synthesis of (−)-vinigrol and provide over 600 mg of material, manifesting the power of macrocyclic stereocontrol and transannular Diels–Alder reaction.
创建时间：
2019-02-18
