five

Crystal structure of IL-17A in complex with compound 26

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Protein Data Bank Japan2024-10-09 更新2026-04-19 收录
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Crystal structure of IL-17A in complex with compound 26 Descriptor: (~{E})-~{N}-[(~{S})-[4,4-bis(fluoranyl)cyclohexyl]-[7-[(1~{S})-2-methoxy-1-[(4~{S})-2-oxidanylidene-4-(trifluoromethyl)imidazolidin-1-yl]ethyl]imidazo[1,2-b]pyridazin-2-yl]methyl]-3-cyclopropyl-2-fluoranyl-prop-2-enamide, Interleukin-17A Authors: Rondeau, J.M, Lehmann, S, Scheufler, C. Deposit date: 2024-06-04 Release date: 2024-10-02 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.068 Å) Cite: Discovery and In Vivo Exploration of 1,3,4-Oxadiazole and alpha-Fluoroacrylate Containing IL-17 Inhibitors. J.Med.Chem., 67, 2024
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2024-06-04
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