Effect of PDE4 inhibition on host gene expression of Mtb-infected mouse lungs.. Mus musculus
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA134885
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资源简介：
Global gene expressions of Mtb-infected mouse lungs were compared between with and without PDE4 inhibitor treatment. A lot of host genes are differentially expressed 21d and 28d post-Mtb infection. PDE4 inhibitor, however, downregulate 10% of genes among those and genes differentially regulated by PDE4 inhibitor are mainly involved immune response. Overall design: Total RNA was isolated from Mtb-infected mouse lungs with or without CC-3052 (25 mg/kg/day) using Trizol reagent and gene profile was analyed using Affymetrix mouse ST 1.0
创建时间：
2010-11-13
