The crystal structure of PDEd in complex with inhibitor-2a
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The crystal structure of PDEd in complex with inhibitor-2a Descriptor: N-(3-chloro-2-methylphenyl)-4-(3,4-dimethyl-7-oxo-2-phenyl-2,7-dihydro-6H-pyrazolo[3,4-d]pyridazin-6-yl)butanamide, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta Authors: Ismail, S, Fansa, E.K, Murarka, S, Wittinghofer, A. Deposit date: 2015-10-13 Release date: 2016-05-04 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Identification of pyrazolopyridazinones as PDE delta inhibitors. Nat Commun, 7, 2016
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2015-10-13
