NCOA3 upregulates MUC4 and MUC1 transcriptionally and through post-translational stability during pancreatic cancer development. Homo sapiens
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA223292
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Stable knock down of NCOA3 in PC cell lines resulted in significant downregulation of the two most differentially expressed MUCs in PC, MUC4 and MUC1. NCOA3 creates pro-inflammatory conditions by up-regulating chemokines like CXCL1, 2, 5 and CCL20 Overall design: Stable Knock down of NCOA3 in CD18/HPAF cell line. RNA was isolated from control and stably transfected cells. Each group has three biological replicate.
创建时间:
2013-10-21



