01_shame.zip

NIAID Data Ecosystem2026-03-13 收录

脓毒症免疫调节

肠道微生物代谢物功能

数据链接：

https://figshare.com/articles/dataset/01_shame_zip/19093172 数据链接链接失效反馈

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资源简介：

Gut microbial metabolite hyodeoxycholic acid targets Toll-like receptor 4/myeloid differentiation factor 2 complex to attenuate macrophage pro-inflammatory activity and defense host against sepsis in mice

创建时间：

2022-01-30

data_sheet_1_Nrf2 Is a Central Regulator of Metabolic Reprogramming of Myeloid-Derived Suppressor Cells in Steady State and Sepsis.PDF

代谢重编程

脓毒症免疫调节

Arising in inflammatory conditions, myeloid-derived suppressor cells (MDSCs) are constantly confronted with intracellular and extracellular reactive oxygen species molecules and oxidative stress. Gene

NIAID Data Ecosystem30

Data_Sheet_1_Siglec-G Deficiency Ameliorates Hyper-Inflammation and Immune Collapse in Sepsis via Regulating Src Activation.docx

脓毒症免疫调节

Src激酶信号通路

Hyper-inflammation during acute phase and sequential hypo-inflammation during immunosuppressive phase in macrophages/monocytes lead to multiorgan failure syndrome and immune collapse of sepsis, in whi

NIAID Data Ecosystem20

Pulmonary and Hepatic Gene Expression following Cecal Ligation and Puncture: Monophosphoryl Lipid A Prophylaxis Attenuates Sepsis-Induced Cytokine and Chemokine Expression and Neutrophil Infiltration

脓毒症免疫调节

炎症基因表达

Polymicrobial sepsis induced by cecal ligation and puncture (CLP) reproduces many of the pathophysiologic features of septic shock. In this study, we demonstrate that mRNA for a broad range of pro- an

PubMed Central10

Table_4_Interleukin-3 protects against viral pneumonia in sepsis by enhancing plasmacytoid dendritic cell recruitment into the lungs and T cell priming.docx

脓毒症免疫调节

病毒性肺炎免疫应答

RationaleSepsis, a global health burden, is often complicated by viral infections leading to increased long-term morbidity and mortality. Interleukin-3 (IL-3) has been identified as an important media

NIAID Data Ecosystem20

Inosine monophosphate and inosine differentially regulate endotoxemia and bacterial sepsis

脓毒症免疫调节

肝脏转录组分析

Inosine monophosphate (IMP) plays a central role in intracellular purine metabolism. How IMP regulates inflammation induced by bacterial products or bacteria is unknown. In this study, we demonstrate

NIAID Data Ecosystem10

01_shame.zip

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