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LncRNAs regulate FBL to facilitate rRNA processing in cancer cells

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE276144
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We identified lncRNA DNAJC3-AS1 can buffer the behavior of FBL condensation in cancer cell. In this study, we preformed the FBL-TurboID-RIP and Single-end Enhanced Cross-linking and Immunoprecipitation (seCLIP) sequencing to to identify candidate RNAs that bind to FBL or its adjacent proteins. The FBL-binding regions distributed throughout the sequence of lncRNAs were also discovered. 1. MOLM-13 and SW480 cells used in the FBL-TurboID-RIP-seq. 2. HEK293T cells used in the FBL-seCLIP.
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2025-03-27
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