Crystal structure of dCK C4S-S74E mutant in complex with UDP and the OR0274 inhibitor
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Crystal structure of dCK C4S-S74E mutant in complex with UDP and the OR0274 inhibitor Descriptor: 4-(4-azanylpyrimidin-2-yl)-N-[2-methyl-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]-1,3-thiazol-2-amine, Deoxycytidine kinase, SODIUM ION, ... Authors: Saez-Ayala, M, Ben-Yaala, K, Betzi, S, Rebuffet, E, Morelli, X. Deposit date: 2022-04-07 Release date: 2023-06-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia. Nat Commun, 14, 2023
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2022-04-07
