<b>Supplementary Table 1: Differential abundant protein values.</b>

Samples were analysed using a Vanquish Neo chromatography setup in-line with an Orbitrap Exploris 480 mass spectrometer and differentially expressed proteins were identified. . The different groups were L-adipocytes alone, Ob-adipocytes alone, L-adipocytes co-cultured with NA-fibroblasts, L-adipocytes co-cultured with As-fibroblasts, Ob-adipocytes co-cultured with NA-fibroblasts and Ob-adipocytes co-cultured with As-fibroblasts