Optimized ribonucleoprotein complexes enhances prime edit-ing efficiency in zebrafish
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP599258
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资源简介：
By co-incubating PE7 protein with La-accessible pegRNAs to form ribonucleoprotein (RNP) complexes and microinjecting these complexes into zebrafish embryos, we achieved up to 15.99% editing efficiency at target locian improvement of 6.81- to 11.46-fold over PE2. Additionally, we observed 16.60% 6-bp insertions and 13.18% 10-bp deletions at the adgrf3b locus, representing a 3.13-fold increase over PE2
创建时间：
2025-07-10
