Annual estimated costs of PEP vaccination per clinic and savings from different pricing strategies.

Savings are calculated from recovered costs from charging for the updated TRC PEP regimen according to the strategies described (see methods for full details) minus costs of PEP delivery (estimated from costs in Table 2) assuming use of 1 mL vials. For all these scenarios we assume there is some wastage and therefore 8×0.1 mL injections are obtained from each 1 mL vial. Costs increase and savings decrease when 0.5 mL vials are used, as illustrated in Figure 3.*For the updated TRC regimen, $2.5 per injection is equivalent to $20 for the full course.**In parts of Tanzania the updated TRC ID regimen has been proposed for implementation.