Little is known about the metabolic state of Mycobacterium tuberculosis (Mtb) inside the phagosome, a compartment inside phagocytes for killing pathogens and other foreign substances. We have develope

NIAID Data Ecosystem40

Additional file 6: of Updated and standardized genome-scale reconstruction of Mycobacterium tuberculosis H37Rv, iEK1011, simulates flux states indicative of physiological conditions

结核分枝杆菌代谢模型

基因组规模代谢网络

An ipython notebook that runs the simulations described in this study. (IPYNB 637Â kb)

Figshare2018-03-03 更新20

Global features of the Mtb metabolic models analyzed in this study.

结核分枝杆菌代谢模型

代谢网络特征分析

DEM: Dead-End Metabolite, URs: Unbounded Reactions, TICs: Thermodynamically Infeasible Cycles, diss. Flux: dissipation flux, MW: Molecular Weight, UD: Undetermined.

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Additional file 3: of Metabolic adaptation of two in silico mutants of Mycobacterium tuberculosis during infection

结核分枝杆菌代谢模型

病原体感染模拟

Improved genome-scale model of Mtb from iOSDD890. (XML 2218 kb)

Figshare2017-11-21 更新30