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DNA demethylation in CD4-CD8-TCR-ab compared to CD8+ T cells in B6.MRL-FASlpr mice

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE155293
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To understand the DNA methylation differences associated with CD4-CD8-TCR-ab (DN) T cells that accumulate in the B6.MRL-FASlpr mouse model we performed reduced representation bisulfite sequencing on these cells compared to CD8+ T cells derived from the lymph nodes. Overall we observed that 95% of the differential CpG were demethylated in DN T cells compared to CD8+ T cells. RRBS on CD4-CD8-TCR-ab compared to CD8+ T cells in B6.MRL-FASlpr mice
创建时间:
2021-01-05
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