Plasma miR-98-5p as a diagnostic biomarker for oxaliplatin-induced neuropathic pain related to NGF and catecholamine dysregulation

This study aimed to identify differentially expressed microRNAs in plasma samples from patients with gastrointestinal cancer treated with oxaliplatin to elucidate the association between the expression levels of miRNA, nerve growth factor, catecholamines, and numeric rating scale score for peripheral neuropathic pain. Overall design: Comparative gene expression profiling analysis of RNA-seq data for plasma samples of patients with gastrointestinal cancer