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Effects of ascorbic acid on topotecan-induced DNA damage in human tumor cells

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE138442
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资源简介:
To investigate mechanisms and differential gene expressions in topotecan-induced DNA damage and effects of ascorbic acid/hydrogen peroxide on these genes in topotecan cytotoxicity in tumor cells MCF-7 breast tumor cells were treated with toptecan and combinations of topotecan and ascorbic acid in RPMI 1640 media containing 10% FBS for various times. Cells wre lysed with Triazol reagent and tyotal RNA was extracted and purified.
创建时间:
2020-08-10
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