Discriminant metabolites observed by 1H-NMR spectroscopy.

The principal discriminant metabolites are ordered according to the loading plots of patients with CLF and ACLF. The number of the metabolite corresponds to the number in the line plot in Figure 2. The chemical shift and multiplicity correspond to those found in the 1H-NMR spectra of the patients’ sera.$ppm: parts per million. s, singlet; b, broad; d, doublet; dd, doublet of doublet; t, triplet, m multiplet; q, quadriplet.#A positive correlation (r) indicates an increased concentration in the ACLF group and a negative correlation indicates a decreased concentration in the CLF group.*A p-value −6 is significant.