Kaposi’s sarcoma-associated herpesvirus (KSHV) latently infects host cells and establishes lifelong persistence as an extra-chromosomal episome in the nucleus. To persist in proliferating cells, the v

NIAID Data Ecosystem30

The human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages.

HIV病毒嗜性机制

病毒基因功能

The human immunodeficiency virus (HIV) genetic determinant(s) responsible for tropism in human T cells or macrophages are not well defined. We studied the role of the HIV type 2 (HIV-2) nef and vpr ge

PubMed Central30

CandidaOrfDB

真菌基因组学

病毒基因功能

CandidaOrfDB contains data from novel, genome-scale tools for the study of Candida albicans, a commensal yeast that is also responsible for frequent superficial and disseminated infections in humans g

知名数据库40

Generation of varicella-zoster virus (VZV) and viral mutants from cosmid DNAs: VZV thymidylate synthetase is not essential for replication in vitro.

病毒基因功能

减毒活疫苗设计

Four overlapping cosmid clones were constructed that contain the complete genome of the attenuated Oka strain of VZV. Transfection of human melanoma cells with the four cosmids resulted in production

PubMed Central1993-08-01 更新30

Human Herpesvirus 6A encoded miRNAs: A role in viral lytic replication

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