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Development of a PD-L1-expressing orthotopic liver cancer model

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE106769
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This study sought to explore the functional significance of PD-L1 expression in tumor cells in the tumor microenvironment. The mouse liver cancer cell line BNL-MEA was transfected with PD-L1 plasmids and stable clones expressing PD-L1 were selected. An orthotopic HCC model was generated by implanting the cells into the subcapsular space of BALB/c mice.
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2020-09-06
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