Ribosome profiling and parallel RNA-seq of S. pombe cells subject to amino acid starvation

NIAID Data Ecosystem2026-05-01 收录

翻译调控

氨基酸饥饿应激反应

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https://www.ncbi.nlm.nih.gov/sra/ERP023462 数据链接链接失效反馈

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Study aims at investigating the translational response of S. pombe cells to amino acid starvation

创建时间：

2023-10-13

Mammalian RNA decay pathways are highly specialized and widely linked to translation

mRNA衰变调控

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RNA decay is crucial for RNA turnover and surveillance, and misregulated in many diseases. This complex system is challenging to study, particularly in mammals, where it remains unclear whether decay

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Polysome seq of Paip1 mutant larva with ERCC-spikein

核糖体分析

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To investigate gene-specific functions of Paip1, we analyzed genes that were preferentially associated with monosome or polysome fractions. Before RNA extraction, Equal amounts of ERCC RNA Spike-in mi

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Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes

翻译调控

核糖体暂停

While translation initiation is extensively regulated, fewer mechanisms are known to control translation elongation. We discovered that prolonged stimulation of macrophages leads to suppression of pro

DataCite Commons2023-02-20 更新70

Pervasive translational regulation of the cell Q1 signalling circuitry underlies mammalian development. Mus musculus

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哺乳动物发育

The degree and dynamics of translational control during mammalian development remain poorly understood. Here we monitored translation of the mammalian genome as cells become specified and organize int

NIAID Data Ecosystem110

Extensive and coordinated control of allele-specific expression by both transcription and translation in Candida albicans

等位基因特异性表达调控

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Though sequence differences between alleles are often limited to a few polymorphisms, these differences can cause large and widespread allelic variation at the expression level. Such allele-specific e

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Ribosome profiling and parallel RNA-seq of S. pombe cells subject to amino acid starvation

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