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PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies [ChIP-seq]

ChEBI2014-10-21 更新2026-07-21 收录

癌症表观遗传学

靶向治疗响应

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-62499 数据链接链接失效反馈

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PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies [ChIP-seq]

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创建时间：

2014-10-21

染色质免疫沉淀测序

癌症表观遗传学

For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf https://www.e

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DNA methylation analysis of esophageal squamous cell carcinoma

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Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic

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Prevention of chromatin destabilization by FACT is crucial for malignant transformation. Prevention of chromatin destabilization by FACT is crucial for malignant transformation

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Histone chaperone FACT is commonly expressed and essential for the viability of transformed but not normal cells and its expression levels correlate with poor prognosis in cancer patients. FACT binds

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PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies [ChIP-seq]

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