Development of serum cell-free miRNA panel for identification of girlish central precocious puberty and premature thelarche

Seek and verify the effectiveness of a subset of cell-free miRNA to identify CPP and PT Overall design: Total 88 subjects including 28 cases of CPP, 37 cases of PT, as well as 23 cases of normal control girls were enrolled as a training cohort. Serum cell-free miRNA was isolated and sequenced.